RT Journal A1 DeMonaco HJ T1 Patient- and physician-oriented web sites and drug surveillance: Bisphosphonates and severe bone, joint, and muscle pain JF Archives of Internal Medicine JO Archives of Internal Medicine YR 2009 FD June 22 VO 169 IS 12 SP 1164 OP 1166 DO 10.1001/archinternmed.2009.133 UL http://dx.doi.org/10.1001/archinternmed.2009.133 AB Postmarketing surveillance and the determination of the real-world safety profile of prescription drugs is arguably flawed. Recent identification of significant adverse effects associated with newly approved prescription drugs support the sometimes-held view that a new system needs to be introduced. The present voluntary system has not provided a sufficient early warning system, and some have called for active systems that probe for potential adverse effects of approved prescription drugs.1 Patient-oriented Web sites may provide an opportunity to identify potential adverse effects early in a drug's postmarket history.