RT Journal A1 Hackam DG, Shojania KG, Spence J, et al T1 Influence of noninvasive cardiovascular imaging in primary prevention: Systematic review and meta-analysis of randomized trials JF Archives of Internal Medicine JO Archives of Internal Medicine YR 2011 FD June 13 VO 171 IS 11 SP 977 OP 982 DO 10.1001/archinternmed.2011.69 UL http://dx.doi.org/10.1001/archinternmed.2011.69 AB The past 30 years have seen substantial improvements in the treatment of most major forms of cardiovascular disease. Despite this, significant gaps in the application of proven treatments remain; these include deficiencies in the use of evidence-based therapies and failure to provide and follow up on recommendations relating to diet, physical activity, and smoking cessation. For example, a large multinational registry of 67 888 patients with established atherosclerosis or multiple cardiovascular risk factors recently reported substantial underuse of statins, antiplatelet agents, and other evidence-based medications.1 Addressing these care gaps is a major goal advocated by scientific associations and embedded in a range of practice guidelines.2- 5