RT Journal
A1 Lasser KE, Murillo J, Lisboa S, et al
T1 Colorectal cancer screening among ethnically diverse, low-income patients: A randomized controlled trial
JF Archives of Internal Medicine
JO Archives of Internal Medicine
YR 2011
FD May 23
VO 171
IS 10
SP 906
OP 912
DO 10.1001/archinternmed.2011.201
UL http://dx.doi.org/10.1001/archinternmed.2011.201
AB Background 
    Patient navigators may increase colorectal cancer (CRC) screening rates among adults in underserved communities, but prior randomized trials have been small or conducted at single sites and have not included substantial numbers of Haitian Creole–speaking or Portuguese-speaking patients.Methods 
    We identified 465 primary care patients from 4 community health centers and 2 public hospital–based clinics who were not up-to-date with CRC screening and spoke English, Haitian Creole, Portuguese, or Spanish as their primary language. We enrolled participants from September 1, 2008, through March 31, 2009, and followed them up for 1 year after enrollment. We randomly allocated patients to receive a patient navigation–based intervention or usual care. Intervention patients received an introductory letter from their primary care provider with educational material, followed by telephone calls from a language-concordant navigator. The navigators offered patients the option of being screened by fecal occult blood testing or colonoscopy. The primary outcome was completion of any CRC screening within 1 year. Secondary outcomes included the proportions of patients screened by colonoscopy who had adenomas or cancer detected.Results 
    During a 1-year period, intervention patients were more likely to undergo CRC screening than control patients (33.6% vs 20.0%; P < .001), to be screened by colonoscopy (26.4% vs 13.0%; P < .001), and to have adenomas detected (8.1% vs 3.9%; P = .06). In prespecified subgroup analyses, the navigator intervention was particularly beneficial for patients whose primary language was other than English (39.8% vs 18.6%; P < .001) and black patients (39.7% vs 16.7%; P = .004).Conclusions 
    Patient navigation increased completion of CRC screening among ethnically diverse patients. Targeting patient navigation to black and non–English-speaking patients may be a useful approach to reducing disparities in CRC screening.Trial Registration 
    clinicaltrials.gov Identifier: NCT01141114