RT Journal A1 Liu C T1 The bundled approach to mrsa surgical site infection prevention: Is the whole greater than the sum of its parts?: comment on “sustained reduction in methicillin-resistant staphylococcus aureus wound infections after cardiothoracic surgery” JF Archives of Internal Medicine JO Archives of Internal Medicine YR 2011 FD January 10 VO 171 IS 1 SP 73 OP 74 DO 10.1001/archinternmed.2010.448 UL http://dx.doi.org/10.1001/archinternmed.2010.448 AB Surgical site infections (SSIs) cause significant patient morbidity and mortality and add $10 billion annually to health care expenditures.1Staphylococcus aureus is the most common pathogen, with methicillin-resistant S aureus (MRSA) accounting for up to 65% of poststernotomy mediastinitis.2 Compared with infections due to methicillin-susceptible S aureus (MSSA), MRSA has been associated with increased mortality, treatment failure, length of hospital stay, and costs.3- 4