RT Journal A1 Wright JT, Jr, Probstfield JL, Cushman WC, et al T1 ALlhat findings revisited in the context of subsequent analyses, other trials, and meta-analyses—reply JF Archives of Internal Medicine JO Archives of Internal Medicine YR 2009 FD October 26 VO 169 IS 19 SP 1806 OP 1818 DO 10.1001/archinternmed.2009.372 UL http://dx.doi.org/10.1001/archinternmed.2009.372 AB We appreciate the favorable comments by Dr Onuigbo on this latest ALLHAT publication.1 We were also impressed by the very positive findings in thiazide-treated patients. ALLHAT was designed to determine whether α-blockers, ACEIs, or CCBs were superior to thiazide-type diuretics (prescribed at an appropriate dosage) as initial therapy for reduction of cardiovascular or renal outcomes.1 While potentially understated, we believe that our overall conclusion that the thiazide-type diuretic was not surpassed is consistent with the data and trial objectives.