RT Journal A1 Kosiborod M, Inzucchi SE, Krumholz HM, Masoudi FA, Goyal A, Spertus JA T1 IS insulin the preferred compound in lowering glucose levels in patients after a myocardial infarction?—reply JF Archives of Internal Medicine JO Archives of Internal Medicine YR 2009 FD September 28 VO 169 IS 17 SP 1633 OP 1638 DO 10.1001/archinternmed.2009.327 UL http://dx.doi.org/10.1001/archinternmed.2009.327 AB While not the main objective of our study (which was to evaluate whether normalization of glucose levels is associated with better survival), the impact of insulin therapy on patient outcomes in a setting of AMI is an important and controversial issue. While treatment thresholds and therapeutic goals remain subjects of intense debate, professional societies currently endorse glucose control in patients with AMI and significant hyperglycemia (blood glucose level >180 mg/dL [to convert to millimoles per liter, multiply by 0.0555]),2 and insulin remains the only reliable way to effectively lower glucose levels in hospitalized patients.