RT Journal A1 Maurer J, Harris KM, Lurie N T1 Reducing missed opportunities to vaccinate adults against influenza: What is realistic? JF Archives of Internal Medicine JO Archives of Internal Medicine YR 2009 FD September 28 VO 169 IS 17 SP 1633 OP 1638 DO 10.1001/archinternmed.2009.287 UL http://dx.doi.org/10.1001/archinternmed.2009.287 AB Despite well-documented evidence regarding effectiveness and safety, uptake of influenza vaccine among adults in the United States falls short of targeted rates.1- 2 Efforts to increase influenza vaccine uptake have focused on reducing the number of so-called missed opportunities, ie, patients who visit health care providers during the fall without being vaccinated.1,3 Yet, the potential effectiveness of provider-based strategies for reducing missed opportunities (eg, standing orders, computerized reminders) may be overstated without consideration of patients' willingness to be vaccinated. We present a more realistic estimate of the potential of such strategies to increase influenza vaccine uptake by quantifying the number of unvaccinated adults most amenable to vaccination during a fall visit to a health care provider.