RT Journal
A1 Golomb BA, Koperski S
T1 New statins also produce fatigue: Spontaneous reporting as a complementary system to increase safety knowledge—reply
JF JAMA Internal Medicine
JO JAMA Internal Medicine
YR 2013
FD February 11
VO 173
IS 3
SP 247
OP 248
DO 10.1001/jamainternmed.2013.2113
UL http://dx.doi.org/10.1001/jamainternmed.2013.2113
AB 
We concur with Tarapués and colleagues. An analysis we conducted of patient reports of muscle problems (including fatigue)1 is in agreement with their Spanish data, extending fatigue adverse effects (AEs) to all statins. These data suggest that risk approximately parallels statin potency, as does our recent analysis of the US Food and Drug Administration AE reports focused on muscle-related AEs,2 although this latter analysis did not expressly address fatigue.