RT Journal A1 Linder JA T1 Antibiotic prescribing for acute respiratory infections—success that's way off the mark: Comment on “a cluster randomized trial of decision support strategies for reducing antibiotic use in acute bronchitis” JF JAMA Internal Medicine JO JAMA Internal Medicine YR 2013 FD February 25 VO 173 IS 4 SP 273 OP 275 DO 10.1001/jamainternmed.2013.1984 UL http://dx.doi.org/10.1001/jamainternmed.2013.1984 AB Imagine for a minute. Imagine in 2013 that the national rate of aspirin use for secondary prevention of coronary artery disease (CAD) is 30%. Imagine that a well-designed, randomized controlled trial of clinical decision support increases the use of aspirin from 30% to 40%. Imagine that the sample size is sufficiently large so that the trial results in a P value of less than .01. Because this was a successful, statistically significant trial, imagine calls to disseminate this intervention with a goal of increasing aspirin use for outpatients with CAD nationwide to 40%.