RT Journal
A1 Grann V, Ashby-Thompson M
T1 Role of genetic testing for screening and prevention for ovarian cancer: Comment on “risk-reducing salpingo-oophorectomy and ovarian cancer screening in 1077 women after brca testing”
JF JAMA Internal Medicine
JO JAMA Internal Medicine
YR 2013
FD January 28
VO 173
IS 2
SP 103
OP 104
DO 10.1001/jamainternmed.2013.2729
UL http://dx.doi.org/10.1001/jamainternmed.2013.2729
AB 
Genetic history of BRCA1/2 mutations identifies women who are at high risk for breast and ovarian cancer and who may benefit from more intensive screening and/or risk-reducing surgeries. BRCA1/2 mutations account for 5% to 10% of all breast cancers in the United States and approximately 10% of ovarian cancers.1 Women with mutations may develop cancers at an early age, leading to psychological distress and loss of both quality and quantity of life. The cost of preventive screening and treatment for BRCA1/2 mutations accounts for approximately $800 million of the more than $8 billion spent each year for treatment of breast and ovarian cancers.2- 3