RT Journal A1 Braillon A T1 Generic competition in a flawed system: Pill them, bill them JF Archives of Internal Medicine JO Archives of Internal Medicine YR 2012 FD October 22 VO 172 IS 19 SP 1522 OP 1523 DO 10.1001/archinternmed.2012.4389 UL http://dx.doi.org/10.1001/archinternmed.2012.4389 AB The license of some corporations to manipulate the system to suit their interests requires an enduring complacency of the system. Recently, the US Food and Drug Administration, despite the lack of evidence for benefit, granted a new marketing authorization for the 23-mg dose of donepezil hydrochloride in the treatment of Alzheimer disease.2 This allows Pfizer to avoid generic competitors, since the patent for donepezil, first approved in 1996, expired in November 2010. Lastly, could this be a reason why so many physicians prescribe their patients with costly medicines when less expensive ones are available?