RT Journal
A1 Bower JK, Lazo M, Juraschek SP, Selvin E
T1 WIthin-person variability in high-sensitivity c-reactive protein
JF Archives of Internal Medicine
JO Archives of Internal Medicine
YR 2012
FD October 22
VO 172
IS 19
SP 1519
OP 1521
DO 10.1001/archinternmed.2012.3712
UL http://dx.doi.org/10.1001/archinternmed.2012.3712
AB 
C-reactive protein (CRP) is a marker of systemic inflammation and cardiovascular disease.1- 3 Based on findings from recent clinical trials, CRP has been recommended as an adjunct screening tool to stratify cardiovascular risk in the general population.4 However, evidence regarding within-person variability of CRP in the general population is limited. Short-term variability in CRP has important implications for its use and interpretation in clinical practice and research studies. Thus, the objective of this study was to evaluate the short-term, within-person variability in CRP measurements and to quantify the impact of repeated testing on CRP-based cardiovascular risk classification.