RT Journal A1 Sullivan M, Ballantyne J T1 CLinician identification of appropriate long-term opioid therapy candidacy—reply JF Archives of Internal Medicine JO Archives of Internal Medicine YR 2012 FD July 23 VO 172 IS 14 SP 1110 OP 1114 DO 10.1001/archinternmed.2012.2565 UL http://dx.doi.org/10.1001/archinternmed.2012.2565 AB We know of no studies that have examined the effects of long-term opioid treatment in employed samples. It is true that employed individuals have maintained a minimum of function despite chronic pain. They may have more flexible or less physically demanding employment, or they may have more rewarding jobs. Any rewards associated with continued function will tend to counteract any functional impairment associated with long-term opioid therapy. One recent study suggested that age and unemployment predicted opioid misuse in a small, mixed sample.1