RT Journal A1 Leach R, Thompson IM T1 THe dilemma of prostate-specific antigen testing JF Archives of Internal Medicine JO Archives of Internal Medicine YR 2012 FD June 11 VO 172 IS 11 SP 835 OP 836 DO 10.1001/archinternmed.2012.1226 UL http://dx.doi.org/10.1001/archinternmed.2012.1226 AB For a man with prostate cancer, treatment decision making is daunting. If the tumor is high grade, decision making may be straightforward because disease-specific mortality is high despite the toxicity of combined therapies that are proved to reduce mortality (eg, radiation and hormonal therapy).1 For a man with an aggressive tumor, while decision making requires considerable thought, information, and support by the treating physician, the possibility of adverse effects often dims when there is an opportunity to improve survival.