RT Journal
A1 Esposito K, Giugliano D
T1 Lifestyle for erectile dysfunction: A good choice
JF Archives of Internal Medicine
JO Archives of Internal Medicine
YR 2012
FD February 13
VO 172
IS 3
SP 296
OP 297
DO 10.1001/archinternmed.2011.785
UL http://dx.doi.org/10.1001/archinternmed.2011.785
AB 
As the authors acknowledge, the minimal clinically important difference in the erectile function domain is accepted to be a 4-point improvement in IIEF-5 score; intuitively, minimal clinically important difference may vary significantly according to the baseline ED severity. A way to circumvent the lack of individual patient data would have been to report how many patients regained sexual function, as indicated by an IIEF-5 score of 22 or higher after lifestyle interventions. In the article by Esposito et al,2 for example, 17 men in the intervention group and 3 in the control group (P = .001) reported an IIEF score of 22 or higher, with 31% of men in the intervention group regaining sexual function. This may be in line with epidemiological evidence3 that physical activity was associated with a 30% lower risk of erectile dysfunction, while obesity was associated with a 30% higher risk of erectile dysfunction.