RT Journal A1 Kassam Z, Hundal R, Marshall JK, Lee CH T1 FEcal transplant via retention enema for refractory or recurrent clostridium difficile infection JF Archives of Internal Medicine JO Archives of Internal Medicine YR 2012 FD January 23 VO 172 IS 2 SP 191 OP 193 DO 10.1001/archinte.172.2.191 UL http://dx.doi.org/10.1001/archinte.172.2.191 AB Clostridium difficile infection (CDI) is the leading cause of nosocomial infection and its rates continue to rise. In the United States, the incidence of CDI tripled between 1996 and 2005 (31 per 100 000 vs 84 per 100 000).1 This has been accompanied by an increase in disease severity, with mortality rates of up to 6.9%.2 In addition, nosocomial CDI increases the cost of otherwise matched hospitalizations by 4-fold.3