RT Journal
A1 Torn M, Rosendaal FR
T1 OPtimal anticoagulation therapy in patients with valvular heart disease or atrial fibrillation—reply
JF Archives of Internal Medicine
JO Archives of Internal Medicine
YR 2009
FD November 23
VO 169
IS 21
SP 2033
OP 2033
DO 10.1001/archinternmed.2009.421
UL http://dx.doi.org/10.1001/archinternmed.2009.421
AB 
With McLeod and Gersh, we believe that, in general, myocardial infarction is not merely an embolic event, but it is thrombotic, and hence “thromboembolic.” Clot formation plays an important role in myocardial infarction, even in severe atherosclerosis. Although not widely used, vitamin K antagonists are effective in preventing myocardial infarction and may well be superior to antiplatelet agents.2 Therefore, we included myocardial infarction as a thromboembolic end point.