RT Journal
A1 Nguyen C, Chan G, Su M
T1 A question of the clinical relevance of determining thrombomodulin level while receiving anticoagulant therapy
JF Archives of Internal Medicine
JO Archives of Internal Medicine
YR 2009
FD November 23
VO 169
IS 21
SP 2031
OP 2031
DO 10.1001/archinternmed.2009.422
UL http://dx.doi.org/10.1001/archinternmed.2009.422
AB 
We would like to thank Lind et al1 for their study on thrombomodulin as a marker for bleeding complications during warfarin treatment. This longitudinal cohort study demonstrates that patients who have high levels of soluble thrombomodulin (sTM) and are receiving long-term vitamin K antagonist therapy appear to be at higher risk of clinically relevant and major bleeding complications. If validated, such a laboratory test would be of great importance and clinical utility in assessing the risk of long-term vitamin K antagonist therapy.