RT Journal A1 Cupertino A, Wick JA, Richter KP, Mussulman L, Nazir N, Ellerbeck EF T1 The impact of repeated cycles of pharmacotherapy on smoking cessation: A longitudinal cohort study JF Archives of Internal Medicine JO Archives of Internal Medicine YR 2009 FD November 9 VO 169 IS 20 SP 1928 OP 1930 DO 10.1001/archinternmed.2009.355 UL http://dx.doi.org/10.1001/archinternmed.2009.355 AB Smoking cessation pharmacotherapy can double quit rates.1 However, smokers often fail after a single quit attempt, and quitting smoking often involves multiple quit attempts over the course of months or years.2- 5 Few studies have tested the impact of providing repeated courses of pharmacotherapy to help smokers recover from relapses and engage in new cessation attempts.6- 11 As part of a study of chronic disease management for smoking cessation, we followed a cohort of smokers that was offered up to 4 courses of pharmacotherapy over 2 years. We examined their continued interest in using pharmacotherapy and the effect of that treatment.