RT Journal
A1 Appleton D, Abbate A, Biondi-Zoccai G
T1 Percutaneous coronary intervention for persistent occlusion of the infarct-related artery: An expanded view of the evidence
JF Archives of Internal Medicine
JO Archives of Internal Medicine
YR 2011
FD November 28
VO 171
IS 21
SP 1962
OP 1963
DO 10.1001/archinternmed.2011.551
UL http://dx.doi.org/10.1001/archinternmed.2011.551
AB 
Abbate et al3 performed a meta-analysis of 10 randomized trials comparing late PCI with medical therapy (including the OAT) in the setting of acute MI and showed an overall survival benefit favoring PCI. There was also a significant improvement in left ventricular ejection fraction and reduced cardiac volumes. Appleton and colleagues4 restricted their meta-analysis to only include trials with persistent total occlusion of the IRA, showing that PCI was associated with a statistically significant improvement in LVEF and cardiac remodeling.