RT Journal
A1 Herzig SJ, Marcantonio ER
T1 ACid suppressive therapy in noncritically ill patients—reply
JF Archives of Internal Medicine
JO Archives of Internal Medicine
YR 2011
FD November 14
VO 171
IS 20
SP 1862
OP 1864
DO 10.1001/archinternmed.2011.514
UL http://dx.doi.org/10.1001/archinternmed.2011.514
AB 
We thank Barletta and El-Ibiary for their insightful comments. We wholeheartedly agree regarding the importance of attempting to identify subgroups of hospitalized, noncritically ill patients with heightened risk for nosocomial GI bleeding to determine if risk is high enough to warrant routine prophylaxis with acid-suppressive medication. Such analyses in critically ill patients were instrumental in identifying high- and low-risk subgroups of patients with numbers needed to treat of 30 and 900, respectively.1 We are currently completing such analyses in our large cohort of hospitalized, noncritically ill patients and hope to shed light on this issue in the future.