RT Journal A1 Mendelson T, Meltzer M, Campbell EG, Caplan AL, Kirkpatrick JN T1 THe proactive management of “relationship with industry” by acc/aha in the creation of our cardiovascular clinical practice guidelines—reply JF Archives of Internal Medicine JO Archives of Internal Medicine YR 2011 FD September 26 VO 171 IS 17 SP 1598 OP 1600 DO 10.1001/archinternmed.2011.426 UL http://dx.doi.org/10.1001/archinternmed.2011.426 AB We appreciate the difficulty organizations face in producing guidelines that garner the trust required to be effective. The adoption of the Council of Medical Specialty Societies (CMSS) policy by the ACC was an important step. However, if one extrapolates the logic of requiring that the chair and majority of guideline committee members be free of conflicts, one could imagine moving to a committee 100% free of COI, especially given our finding of a substantial pool of nonconflicted experts with guidelines experience. The counterargument is that excluding crucial experts will diminish the quality of guidelines. But why not ask these crucial individuals to choose between guideline-writing participation and industry relations? Divestiture of industry affiliation is required of key society leaders in the CMSS policy.2 The same could be applied to guidelines committees, which are no less important.