RT Journal A1 Dentali F, Guasti L T1 ARe statins effective in high-risk primary prevention? JF Archives of Internal Medicine JO Archives of Internal Medicine YR 2010 FD December 13 VO 170 IS 22 SP 2042 OP 2044 DO 10.1001/archinternmed.2010.458 UL http://dx.doi.org/10.1001/archinternmed.2010.458 AB Findings of this meta-analysis are consistent with the results of a previous meta-analysis that included individuals without clinically manifest coronary heart disease.2 Furthermore, their methodology is accurate, and the authors obtained relevant unpublished data from the authors of original studies. Thus, their results appear to be reliable questioning the role of statins in primary prevention.