RT Journal A1 Levis S, Xu P, Doerge DR, Krischer J T1 SOy isoflavone supplementation in menopausal women—reply JF Archives of Internal Medicine JO Archives of Internal Medicine YR 2011 FD December 12 VO 171 IS 22 SP 2067 OP 2068 DO 10.1001/archinternmed.2011.583 UL http://dx.doi.org/10.1001/archinternmed.2011.583 AB A total of 66 randomized participants did not complete the study (23 in the soy isoflavone group and 43 in the placebo group).1 A comparable number of women in each group reported moving out of state, having a sick family member, a new job, or a desire to eat soy products as the reason to discontinue their participation. Although there was a marked difference in the proportion of participants who were no longer interested in participating in the study or were lost to follow-up (16 [19%] in the soy isoflavone group and 30 [34%] in the placebo group), we did not find any objective measures that could explain this difference.