RT Journal A1 Wuerstle MC, Van Den Eeden SK, Poon K, et al T1 COntribution of common medications to lower urinary tract symptoms in men JF Archives of Internal Medicine JO Archives of Internal Medicine YR 2011 FD October 10 VO 171 IS 18 SP 1680 OP 1682 DO 10.1001/archinternmed.2011.475 UL http://dx.doi.org/10.1001/archinternmed.2011.475 AB Through effects on detrusor muscle and urinary sphincter function, several categories of prescription drugs can worsen LUTS,2- 3 including antidepressants, antihistamines, bronchodilators, anticholinergics, and sympathomimetics.4 By increasing urine volume, diuretics are also associated with LUTS.5- 6 Because their prevalence of use rises with patient age, prescription drugs may contribute to the age-related increase in LUTS.7- 8