RT Journal A1 Bjelakovic G, Gluud C T1 Vitamin and mineral supplement use in relation to all-cause mortality in the iowa women's health study: Comment on “dietary supplements and mortality rate in older women” JF Archives of Internal Medicine JO Archives of Internal Medicine YR 2011 FD October 10 VO 171 IS 18 SP 1633 OP 1634 DO 10.1001/archinternmed.2011.459 UL http://dx.doi.org/10.1001/archinternmed.2011.459 AB Many studies have been conducted to verify the assumed beneficial effects of vitamin and mineral supplements. Although the results of epidemiologic observational studies almost uniformly have been positive, the results of individual randomized clinical trials undertaken to corroborate this hypothesis have remained largely inconclusive. Only through the systematic review of several randomized clinical trials have we gained the power and the precision to detect clinical harms and benefits.