RT Journal A1 Grady D T1 Conservative use of prescription drugs: Comment on “communicating uncertainties about prescription drugs to the public” JF Archives of Internal Medicine JO Archives of Internal Medicine YR 2011 FD September 12 VO 171 IS 16 SP 1470 OP 1470 DO 10.1001/archinternmed.2011.370 UL http://dx.doi.org/10.1001/archinternmed.2011.370 AB And unfortunately, after being informed that new drugs (which don't have a track record of safety) may be more dangerous than older drugs, and that drugs shown to improve surrogate outcomes may not actually prevent disease, a large proportion of persons still chose new drugs—and those without evidence of clinical benefit. Perhaps selecting the most clinically effective and safe drug should be the responsibility of properly trained clinicians.