RT Journal A1 Warner Stevenson L T1 “A little learning is a dangerous thing” JF Archives of Internal Medicine JO Archives of Internal Medicine YR 2011 FD September 12 VO 171 IS 16 SP 1494 OP 1495 DO 10.1001/archinternmed.2011.272 UL http://dx.doi.org/10.1001/archinternmed.2011.272 AB Published 300 years later, 2 articles in this issue of the Archives re-examine our basis of evidence for cardiac resynchronization therapy (CRT).2- 3 They provide vivid demonstration of how we may be intoxicated by the enthusiastic presentations of new trials2 and how we may be rendered sober again by deeper analysis of the collective experience3 as we seek to translate those trials for the patients who rely on our wisdom. It is remarkable that these lessons can be clearly exemplified even in relation to CRT, which offers carefully selected patients one of the most effective therapies for heart failure in terms of quality of life, freedom from hospitalization, and survival.