Editorial |

Aortic Stenosis:  A New Face for an Old Disease

Joseph S. Alpert, MD
Arch Intern Med. 2003;163(15):1769-1770. doi:10.1001/archinte.163.15.1769.
Text Size: A A A
Published online


WHEN I WAS a second-year medical student in the 1960s, one of the first patients I was shown was a man with severe aortic stenosis secondary to rheumatic heart disease. I still remember this patient's face and the distinctive, rough, systolic ejection murmur that filled systole, obliterating the second heart sound. Since then, rheumatic cases of aortic stenosis have become rare, but severe aortic stenosis is still one of the commonest causes of valvular heart disease seen in hospitalized patients. In the more than 30 years since I saw my first patient with aortic stenosis, much has been learned concerning the pathophysiology of this condition. Indeed, there are studies currently under way seeking to alter the pathological sequence in this disease that eventually leads to aortic valve replacement.

Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
First page PDF preview





Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment


Some tools below are only available to our subscribers or users with an online account.

Web of Science® Times Cited: 7

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

Articles Related By Topic
Related Topics
PubMed Articles

The Rational Clinical Examination
Evidence Summary and Review 1

The Rational Clinical Examination
Clinical Scenario