0
Comments, Opinions, and Brief Case Reports |

Association Between Folic Acid Food Fortification and Hypertension or Preeclampsia in Pregnancy

Joel G. Ray, MD, FRCPC, MSc; Muhammad M. Mamdani, PharmD, MA, MPH
Arch Intern Med. 2002;162(15):1776-1777. doi:.
Text Size: A A A
Published online

Extract

From April 1990 to March 2000, the overall rate of preeclampsia did not significantly change before (3.8%) and after (3.7%) the introduction of a mandatory Canadian folic acid food fortification program in January 1998.

Ray  JGLaskin  CA Folic acid and homocyst(e)ine metabolic defects and the risk of placental abruption, pre-eclampsia and spontaneous pregnancy loss: a systematic review. Placenta. 1999;20519- 529
National High Blood Pressure Education Program Working Group on High Blood Pressure in Pregnancy, Report on high blood pressure in pregnancy. Am J Obstet Gynecol. 1990;1631691- 1712
Not Available, Report of the National High Blood Pressure Education Program Working Group on High Blood Pressure in Pregnancy. Am J Obstet Gynecol. 2000;183S1- S22
Dekker  GSibai  B Primary, secondary, and tertiary prevention of pre-eclampsia. Lancet. 2001;357209- 215
Dawson  LEPham  BHunter  AG Low rate of adequate folic acid supplementation in well-educated women of high socioeconomic status attending a genetics clinic. CMAJ. 2001;1641149- 1150
McMahon  MJAnanth  CVListon  RM Gestational diabetes mellitus: risk factors, obstetric complications and infant outcomes. J Reprod Med. 1998;43372- 378
Ray  JGBurrows  RFBurrows  EAVermeulen  MJ MOS HIP: McMaster Outcome Study of Hypertension in Pregnancy. Early Hum Dev. 2001;64129- 143
Homocysteine Lowering Trialists' Collaboration, Lowering blood homocysteine with folic acid-based supplements: meta-analysis of randomised trials. Indian Heart J. 2000;52S59- S64
Ray  JGVermeulen  MJBoss  SCCole  DE Increased red cell folate concentrations in women of reproductive age after Canadian folic acid food fortification. Epidemiology. 2002;13238- 240
Figures in this Article

Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
/>
First page PDF preview

Figures

Place holder to copy figure label and caption

Monthly rate of preeclampsia-eclampsia (lower curve) or any hypertension in pregnancy (upper curve) before and after folic acid food fortification (dashed line). ARIMA indicates autoregressive integrated moving average.

Graphic Jump Location

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Web of Science® Times Cited: 14

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

Articles Related By Topic
Related Topics
PubMed Articles
Jobs
brightcove.createExperiences();