Vertical transmission of human immunodeficiency virus type 1 (HIV-1) results from the interplay of virologic, immunologic, and pharmacological factors. Thus, HIV-1 variants are under selection for their ability to grow to high levels within the mother and for their ability to initiate a new infection within the infant. The use of antiretroviral drugs during pregnancy adds another level of selection to this process, wherein the ability to efficiently grow in the presence of the drug may select for mutants with altered fitness for spreading to infants.
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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature
Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal
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