Volume 4 of Osier and McCrae's Modern Medicine deals with the diseases of the circulatory system, of the blood, of the lymphatic system and spleen, of the ductless glands, and with vasomotor and trophic disorders. It covers what is included in Volume 4, and in part of Volume 6 of the first edition. The general changes in typography, etc., have already been mentioned in the review of the first two volumes of the new System, in Volume XIV, page 608, of this journal.
Most of the chapters have been shortened to some extent, chiefly by the omission of the historical paragraphs, by the omission of discussions of the older theories as to the etiology and pathogenesis of various diseases, which as a result of recent advances in knowledge are now of historical interest only, and frequently by the omission or abbreviation of illustrative case reports. Many minor changes have been