Through the cooperation of the Research Laboratory I was able to give a series of patients suffering from lobar pneumonia an antipneumococcus serum, and although the results were somewhat inconclusive, it seems desirable to publish them.
The series includes practically all of the pneumonia patients admitted to the service of the Second Medical Division of New York Hospital during the period of the test. This division receives all medical patients admitted to the hospital on the even days of the month, while those admitted on the odd days go to the first division. Although this method of assignment does not give a strict alternation of patients, yet it seemed justifiable to use the patients on the first division as controls, inasmuch as none of them received any serum.
The serum was taken from a horse immunized against many strains of pneumococci.1 Usually it was injected directly into a