The findings reported in this paper are the result of work suggested by Dr. H. D. Singer, director of the institute, and begun by A. F. Wussow in this laboratory. Pighini1 and Statuti2 claimed from their data that the metabolism of dementia praecox was not normal. Wussow3 and Barnes4 did not obtain results that confirmed the findings of Pighini and Statuti. Folin5 found no evidence of an abnormal metabolism in dementia praecox.
The plan of the tests was to determine the income and the outgo of nitrogen, sulphur, phosphorus, calcium and magnesium in cases of dementia praecox. Tests were made at various times of the year and various diets were used (Table 1).The method of preparing and preserving the food used in these tests made it possible to have but one sample of food for analysis and to give the patient a constant