0
ARTICLE |

THE RELATION OF THE HYPOPHYSIS TO GROWTH AND THE EFFECT OF FEEDING ANTERIOR AND POSTERIOR LOBE

DEAN D. LEWIS, M.D.; JOSEPH L. MILLER, M.D.
Arch Intern Med (Chic). 1913;XII(2):137-145. doi:10.1001/archinte.1913.00070020023002.
Text Size: A A A
Published online

As observed by the clinician, there are two clinical entities, both disturbances of growth, ascribed to disturbed functioning of the hypophysis. One is acromegaly, characterized by enlargement of certain bones; the other, delayed development with adiposity and genital atrophy. When the former occurs in early life, gigantism results; when it first appears after maturity, enlargement of only certain portions of the bony skeleton is observed. In the other type, when the disturbance appears in early life, there is delayed skeletal development, with adiposity and failure of sexual evolution; when it appears after maturity, adiposity and sexual atrophy.

Pierre Marie, in 1886, first called attention to the relation between acromegaly and the hypophysis, although Carl von Langer in 1872, in an anatomical study of giants, referred to a certain type with enlarged sella turcica. The observations of Marie have been confirmed, until at present it is generally conceded that acromegaly

Topics

Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
/>
First page PDF preview

Figures

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();