Arch Intern Med (Chic). 1913;XI(5):469-484. doi:10.1001/archinte.1913.00060290003001.
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The importance of local disturbances in circulation in the etiology of gastric and duodenal ulcer appeals to be a well established fact with the majority of those who have made a close anatomical study of this condition. Still this view seems to be far from generally accepted. Only a short time ago a special committee was organized in Germany for the collective investigation of the causation of ulcer of the stomach. In its circular this committee makes the following statement: "The nature of ulcer of the stomach has not yet been explained. Even if we have been successful in producing gastric ulcers experimentally, with all their characteristic signs, yet the etiology of gastric ulcer in man is practically unknown.'' Schütz1 says quite recently:

We still have very incomplete and inaccurate ideas as to its etiology and its development and in this regard have to resort to hypotheses. Even


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