0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

LEUKOCYTIC ENZYMES IN LEUKEMIA IN NEUTRAL MEDIA

ROGER S. MORRIS, M.D.; THOMAS R. BOGGS, M.D.
Arch Intern Med (Chic). 1911;VIII(6):806-819. doi:10.1001/archinte.1911.00060120092005.
Text Size: A A A
Published online

The enzymes which have been found in the leukocytes in leukemia are of three kinds—proteolytic, oxidizing and lipolytic.

A protease has been reported in chronic myeloid leukemia by a number of observers. Erben,1 in studying autolysis of leukemic blood, obtained evidence of protein digestion which he suspected was due to an enzyme contained in the neutrophilic cells; he was, however, unable to demonstrate the source of the ferment satisfactorily, but assumed that the neutrophils furnished it, since he could find no autolysis in lymphoid leukemia. Schumm2 demonstrated that the incoagulable nitrogen ("albumoses") of leukemic blood resulted from enzymotic activity, though the source of the enzyme was not stated. The occurrence of autolysis in the blood of chronic myeloid leukemia was further confirmed by Pfeiffer,3 who studied material from two cases. He also showed that bloods presenting a leukocytosis underwent autolysis, though less rapidly than leukemic bloods,

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();