The observations recorded in this paper are a continuation of work briefly alluded to in a previous article.1 The purpose of this work is to discover whether or not the hydrochloric acid of the gastric juice is diminished in cases of infantile atrophy.
In the article on the causation of atrophy referred to above, I suggested a theory of the cause of infantile atrophy based on the results of secretin determinations in atrophic and well-nourished infants.
The secretin production from the cases of atrophy which I examined was much diminished compared with that from a limited number of well-nourished infants. The explanation for this diminution in secretin in atrophic infants was sought for higher up in the digestive tract. It seemed improbable that the condition was a primary one in the small intestines. The normal stimulus, according to Bayliss and Starling, which causes the transformation of prosecretin