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EXPERIMENTAL LUNG ANTHRACOSIS

LEWIS SAYRE MACE, M.D.
Arch Intern Med (Chic). 1910;VI(5):532-535. doi:10.1001/archinte.1910.00050330067005.
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Recent work, especially in France and Germany, has again opened the question of the origin of lung anthracosis. Calmette and others of his school at Lille have observed it in animals fed with charcoal, but failed to find a true parenchymatous anthracosis when the substance was merely inhaled, the stomach absorption being excluded by cutting and tying the esophagus. They therefore concluded that lung anthracosis is usually of intestinal origin, and believe that the continual passage of particles through the lymphatic system to the right heart in time breaks down the resistance of this natural barrier to the progress of foreign bodies from the intestine to the general circulation. Drawing attention to the analogy between lung anthracosis and lung tuberculosis, they point out that the latter may be of intestinal origin as well as the former. This analogy tremendously increases the importance of the work, and has led many others

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