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A STUDY OF CASES OF HODGKIN'S DISEASE AND CERTAIN ALLIED CONDITIONS

HOWARD T. KARSNER, M.D.
Arch Intern Med (Chic). 1910;VI(2):175-195. doi:10.1001/archinte.1910.00050300056005.
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The following observations were thought to be of value because they add to the number of reported cases of a somewhat rare disease and because I believe that they throw some light on an obscure and much-discussed subject. The report of a case of Hodgkin's disease running an acute course, the diagnosis of two other cases by the examination of lymph-nodes removed surgically, the report of a case of tuberculous lymphadenitis whose histologic appearance closely simulated that of Hodgkin's disease, and a case of Hodgkin's disease that appears to have undergone sarcomatous transformation, form a series from which, with other observations from the literature, certain well-supported conclusions may be drawn.

I shall not go into a wearying presentation of the literature, which has been reviewed most completely in the papers by Reed,1 Longcope,2 and Yamasaki,3 and in some of the more extensive articles such as those

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