0
ARTICLE |

TROPHONEUROTIC CHANGES IN BONES AND JOINTS IN LEPROSY

FRANCIS HARBITZ, M.D.
Arch Intern Med (Chic). 1910;VI(2):147-169. doi:10.1001/archinte.1910.00050300028003.
Text Size: A A A
Published online

It is well recognized that in leprosy, especially its anesthetic form, marked deformities of the hands and feet may develop. Such cases are generally designated as "lepra mutilans." Many, perhaps the majority of these cases, are dependent on ulceration, necrosis, and chronic suppurative inflammation, which in turn are indirectly due to a chronic leprous neuritis with its accompanying anesthesia and analgesia. Necroses or ulcers form, phalanges gradually slough off, and finally the characteristic, clubbed hands and feet of leprosy are formed. The accompanying illustrations of such hands and feet show their appearance in some very pronounced cases. This explanation does not hold in all cases, however, as some of these deformities are to be ascribed to a peculiar trophoneurotic influence which is probably directly exerted by the neuritis on the tissues, especially those of the osseous system, and which may result in atrophy of bone of characteristic

Topics

Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
/>
First page PDF preview

Figures

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();