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February 1908, Vol I, No. II >
ARTICLE | February 1908

THE PRESENT STATUS OF OUR KNOWLEDGE OF THE CHEMISTRY OF THE PROCESSES OF IMMUNITY.

H. GIDEON WELLS, M.D.
Arch Intern Med (Chic). 1908;I(II):262-276. doi:10.1001/archinte.1908.00050020127006.
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It is extremely doubtful if, in the entire range of recent medical literature, there can be found a set of articles that contradict one another more flatly than do those that report the attempts so far made to learn something concerning the chemical nature and action of the substances concerned in the reactions of immunity. After contrasting one report with another, the product seems to be entirely neutral, or better, amphoteric, for one's conclusions will depend largely on one's choice of indicator. He may accept the word of the last disputant, or believe only the work of those whom he knows, or he may, with considerable propriety, be skeptical concerning most of the positive results and claims. Indeed, after a first review of the literature on this subject, the only hope seems to lie in the thought that "where there is so much smoke there must be some fire;" but

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AAM 2010;304:1493-1495.
All you need to read in the other general journals
BMJ 2010;341:c5893-c1494.
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