Slit-lamp examination of the lens was
carried out in 32 hypoparathyroid patients and in 25 thyroidectomized
normocalcemic control patients. There
was a high prevalence of lenticular
opacities in both groups. Opacities sufficiently severe to be visible on clinical
examination were present in half the
hypoparathyroid patients and in two
subjects of the control group. In eight
of the hypoparathyroid patients, the lens
changes consisted of one or more discrete layers of opacity in the peripheral
cortex; this appearance, regarded as a
typical lesion of hypoparathyroidism,
was also seen in one control patient.
The prevalence of typical lens changes
and of cataracts requiring surgery increased with the duration of hypocalcemia.