We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Definition of Screening Status in Case-Control Studies of the Efficacy of Endoscopy

Noel S. Weiss
Arch Intern Med. 1996;156(10):1113. doi:10.1001/archinte.1996.00040041113013.
Text Size: A A A
Published online


By using records of the US Department of Veterans Affairs, Müller and Sonnenberg1 were able to undertake a very large case-control study of the efficacy of endoscopic screening for colorectal cancer. However, the disadvantage of using data from this source is the inability to characterize individual endoscopic examinations regarding their intent, ie, screening vs response to a symptom or sign. The inclusion of nonscreening examinations in the analysis would serve to minimize the estimated efficacy of screening, since patients with fatal colorectal cancer would be far more likely to have had an examination of this type than controls without colorectal cancer. Recognizing this potential bias, Müller and Sonnenberg restricted their comparison to examinations performed before those that led to the diagnosis of colorectal cancer. However, this approach has its own drawbacks, for it will effectively ignore the most relevant portion of the screening history of those fatal cases in which


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.