0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

Statistical Power and Polyvalent Immunoglobulin

Jeff Whittle
Arch Intern Med. 1990;150(8):1760. doi:10.1001/archinte.1990.00040031760034.
Text Size: A A A
Published online

To the Editor.—  In a report on their randomized trial of the use of polyvalent immunoglobulin (IgG) for prevention of cytomegalovirus infection after renal transplantation,1 Kasiske et al report that incidence rates of cytomegalovirus infection and moderately severe cytomegalovirus infection were not significantly different between the control group (84% and 77%, respectively) and the group treated with intravenous IgG (67% and 53%, respectively). I was not surprised that these decreases of 21% and 31% from baseline were not significant, since the sample size was quite small (15 treated with intravenously administered IgG, 13 controls), but I was surprised by their statement that this study had a power of .86 to detect a (clinically) significant difference in infection incidence and a power of .91 to detect such a difference in moderately severe infection rates.I therefore worked back from their data to calculate what they had considered to be a significant difference in infection

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Figures

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();