0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Comments, Opinions, and Brief Case Reports |

Primary Infection With a Multidrug-Resistant HIV-1 Strain

Sophie Morelon, MD; Martine Harzic, MD; Marie-Laure Chadenat, MD; Caroline Dupont, MD; Elisabeth Rouveix, MD
Arch Intern Med. 2001;161(18):2259-2260. doi:.
Text Size: A A A
Published online

Extract

Drug resistance may be the main cause of antiretroviral treatment failure in human immunodeficiency virus (HIV) infection. Drug-resistant mutations have been described for all 3 classes of antiretroviral drugs. The first case of sexual transmission of a multidrug-resistant variant (MDR) was published in 1998.1 We report a new case.

Hecht  FMGrant  RMPetropoulos  CJ  et al.  Sexual transmission of an HIV-1 variant resistant to multiple reverse transcriptase and protease inhibitors. N Engl J Med. 1998;339307- 311
Ngo-Giang-Huong  NDeveau  CDa Silva  I  et al.  Proviral HIV-1 DNA in subjects followed since primary HIV-1 infection who suppress plasma viral load after one year of highly active antiretroviral therapy. AIDS. 2001;151- 9
Boden  DHurley  AZhang  A  et al.  HIV-1 drug resistance in newly infected individuals. JAMA. 1999;2821135- 1141
Little  SJDaar  ESD'Aquila  RT  et al.  Reduced antiretroviral drug susceptibility among patients with primary HIV infection. JAMA. 1999;2821142- 1149
Tamalet  CPasquier  CYahi  N  et al.  Prevalence of drug-resistant mutants and virological response to combination therapy in patients with primary HIV-1 infection. J Med Virol. 2000;61181- 186
Yerly  SKaiser  LRace  EBru  J-PClavel  FPerrin  L Transmission of antiretroviral-drug-resistant HIV-1 variant. Lancet. 1999;354729- 733

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Articles Related By Topic
Related Collections
PubMed Articles
Jobs
brightcove.createExperiences();