Editor's Correspondence |

Underrepresentation of the Risk and Incidence of Anaphylaxis to Foods

Scott H. Sicherer, MD; Hugh A. Sampson, MD; S. Allan Bock, MD; Anne Muñoz-Furlong
Arch Intern Med. 2001;161(16):2046-2047. doi:.
Text Size: A A A
Published online


We were puzzled by the review article on anaphylaxis by Neugut et al1 recently published in the ARCHIVES. The authors estimated that anaphylaxis to foods, drugs, latex, and insect stings may affect 1.2% to 15.0% of the US population. Risks and rates of idiopathic, exercise-induced, and other causes of anaphylaxis were not included in this estimate. They point out numerous limitations in their analysis, primarily stemming from variations in the definition of anaphylaxis and the lack of studies performed on unselected populations. Although we recognize these limitations, we were most surprised by their apparent underestimate of the impact of food-induced anaphylaxis. In the abstract, the rate of food-induced anaphylaxis was reported as 0.0004% and the minimal population at risk was reported as 1099 compared with minimal estimates of 1.9 million for penicillin, 1.36 million for insect stings, and 22 000 for radiocontrast media.

Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
First page PDF preview





September 10, 2001
Alfred I. Neugut, MD, PhD; Rachel L. Miller, MD; Anita Ghatak, MPH
Arch Intern Med. 2001;161(16):2047. doi:.
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment


Some tools below are only available to our subscribers or users with an online account.

Web of Science® Times Cited: 2

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

See Also...
Articles Related By Topic
Related Topics
PubMed Articles
The allergic emergency - management of Anaphylaxis. J Dtsch Dermatol Ges Published online Mar 27, 2014.;