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Comments, Opinions, and Brief Case Reports |

Granulomatous Mastitis: An Uncommon Cause of Breast Abscess

Jacques Pouchot, MD; Elisabeth Foucher, MD; Marie Lino, MD; Janine Barge, MD; Philippe Vinceneux, MD
Arch Intern Med. 2001;161(4):611-612. doi:.
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Granulomatous mastitis (GM) is a benign inflammatory breast disease of unknown origin that usually affects young women of childbearing age.13 Patients usually present with a progressive onset of a breast lump and there is no history of infection or trauma. The breast lesion is of variable size, usually unilateral, firm, ill defined, and mildy tender. Sometimes an associated locally inflammatory reaction and even a sinus formation are present; nipple retraction is common.13 Enlargement of axillary lymph nodes is frequent, and many have reported cases of patients who were thought to have had a malignant disease and that in some instances resulted in inappropriate radiotherapy and wide resection of breast tissue.1

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Histological characteristics of the mass in the right breast. There is extensive granulomatous inflammation (arrows) with epithelioid histiocytes and multinucleated giant cells (inset at right). The inflammatory infiltrate also contained numerous plasmocytes (inset at left).

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