0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

Is Obesity Related to Microvascular and Macrovascular Complications in Diabetes?  The Wisconsin Epidemiologic Study of Diabetic Retinopathy

Ronald Klein, MD, MPH; Barbara E. K. Klein, MD, MPH; Scot E. Moss, MA
Arch Intern Med. 1997;157(6):650-656. doi:10.1001/archinte.1997.00440270094008.
Text Size: A A A
Published online

Background:  There are few epidemiological data describing the relationship of obesity to the incidence of microvascular and macrovascular complications in patients with diabetes.

Methods:  In a population-based study performed in southern Wisconsin, 1370 persons diagnosed as having diabetes when they were 30 years of age or older (mean[±SD] age, 66.6±11.3 years) participated in a baseline examination, 987 in a 4-year follow-up examination, and 533 in a 10-year follow-up examination. Height and weight were measured using standard protocols. Individuals were characterized as underweight, normal weight, overweight, and obese by body mass index (expressed as weight in kilograms divided by the square of the height in meters) status. Outcomes included incidence and progression of retinopathy, incidence of gross proteinuria, incidence of lower-extremity amputation, and death due to ischemic heart disease, death due to stroke, and all-cause mortality.

Results:  The prevalence of being obese was 25.2%. After other risk factors were controlled for, being underweight was associated with higher incidence of diabetic retinopathy, death from stroke, and all-cause mortality. Body mass was not associated with progression of retinopathy, incidence of gross proteinuria, amputation of a lower extremity, or death due to ischemic heart disease.

Conclusions:  These data suggest that obesity in persons with older-onset diabetes is not related to the long-term incidence of microvascular and macrovascular complications.Arch Intern Med. 1997;157:650-656

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Figures

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Web of Science® Times Cited: 37

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();