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Neisseria subflava Bacteremia in a Neutropenic Patient

Pere Domingo, MD; Pere Coll, MD; Pablo Maroto, MD; Guillem Verger, MD; Guillem Prats, MD
Arch Intern Med. 1996;156(15):1762-1765. doi:10.1001/archinte.1996.00440140204024.
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Neisseria species other than Neisseria meningitidis and Neisseria gonorrhoeae are commonly found as saprophytes in the upper respiratory tract and have been called "nonpathogenic Neisseriae."1 However, some of these usually nonpathogenic species, such as Neisseria subflava, Neisseria flavescens, Neisseria mucosa, Neisseria sicca, and Neisseria lactamica, have caused disease in both normal and immunocompromised hosts.2,3 We recently cared for a patient who presented with N subflava bacteremia while neutropenic because of anticancer chemotherapy.

Report of a Case.  An 18-year-old woman was admitted to the hospital because of a 3-day history of fever and malaise. Her medical history was remarkable for Ewing sarcoma diagnosed 2 years before, and she was being treated with cycles of cisplatin, the last of which was administered 10 days before admission. Her temperature was 38.5°C; respiratory rate, 22/min; heart rate, 118/min; and blood pressure reading, 100/60 mm Hg. Physical examination on admission disclosed a


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